Dr. Hou received his B.S. and M.S. from Northeast Agricultural University in 1997 and 2000, respectively, and his Ph.D from Zhejiang University in 2004. After postdoctoral research at National University of Singapore and Temasek Life Science Laboratory from 2006-2011, he joined SCBG as a principal investigator.
Phytohormones and their cross-talks play vital roles during various developmental processes and environmental challenges in plants. It is important to enhance the precise understanding of the mechanisms engaged by phytohormones in modulating plant growth and development. Furthermore, these findings would also provide potential methods for improving crop economical traits.
Our studies use Arabidopsis and soybean as research materials and focus on the following projects:
1. As an important plant hormone, gibberellins (GAs) control various crucial aspects in plant life cycle including germination, stem elongation, flower development, defense response and stress response. We are interested in revealing the molecular mechanism of GA signaling pathway and finally elucidate how GA functions in plants; Meanwile, we are investigating the molecular mechanism of cross-talks between phytohormones and elucidating their roles in plant development and stress responses.
2. We are also interested in investigating the molecular mechanism of plant seed development, maturation, and germination.
1. Yuhua Yang#, Xu Liu#, Wenbin Zhang, Qian Qian, Limeng Zhou, Shu Liu, Yuge Li, and Xingliang Hou* (2021) Stress response proteins NRP1 and NRP2 are pro-survival factors that inhibit cell death during ER stress. Plant Physiology DOI: 10.1093/plphys/kiab335
2. Xiaoming Li#, Chao Fang#, Yongqing Yang#, Tianxiao Lv#, Tong Su#, Liyu Chen, Haiyang Nan, Shichen Li, Xiaohui Zhao, Sijia Lu, Lidong Dong, Qun Cheng, Yang Tang, Meilan Xu, Jun Abe, Xingliang Hou, James L Weller, Fanjiang Kong*, Baohui Liu* (2021) Overcoming the genetic compensation response of soybean florigens to improve adaption and yield at low latitudes. Current Biology DOI: 10.1016/j.cub.2021.06.037
3. Chunyu Zhang, Qian Qian, Xiang Huang, Wenbin Zhang, Xu Liu, and Xingliang Hou* (2021) NF-YCs modulate histone variant H2A.Z deposition to regulate photomorphogenic growth in Arabidopsis. Journal of Integrative Plant Biology 63, 1120-1132
4. Wenbin Zhang, Yang Tang, Yilong Hu, Yuhua Yang, Jiajia Cai, Hailun Liu, Chunyu Zhang, Xu Liu, and Xingliang Hou* (2021) Arabidopsis NF-YCs play dual roles in repressing brassinosteroid biosynthesis and signaling during light-regulated hypocotyl elongation. The Plant Cell DOI: 10.1093/plcell/koab112
5. Lin Yue#, Xiaoming Li#, Chao Fang#, Liyu Chen#, Hui Yang#, Jie Yang , Zhonghui Chen, Haiyang Nan , Linnan Chen , Yuhang Zhang , Haiyang Li, Xingliang Hou, Zhicheng Dong, James L. Weller, Jun Abe, Baohui Liu, and Fanjiang Kong* (2021) FT5a interferes with the Dt1‐AP1 feedback loop to control flowering time and shoot determinacy in soybean. Journal of Integrative Plant Biology 63, 1004-1020
6. Qian Qian, Yuhua Yang, Wenbin Zhang, Yilong Hu, Yuge Li, Hao Yu, and Xingliang Hou* (2021) A novel Arabidopsis gene RGAT1 is required for GA-mediated tapetum and pollen development. New Phytologist 231, 137-151
7. Yilong Hu#, Limeng Zhou#, Yuhua Yang, Wenbin Zhang, Zhonghui Chen, Xiaoming Li, Qian Qian, Fanjiang Kong, Yuge Li, Xu Liu, and Xingliang Hou* (2021) The gibberellin signaling negative regulator RGA-LIKE3 promotes seed storage protein accumulation. Plant Physiology 185, 1697-1707
8. Hailun Liu#, Yuge Li#, Yilong Hu, Yuhua Yang, Wenbin Zhang, Ming He, Xiaoming Li, Chunyu Zhang, Fanjiang Kong, Xu Liu, and Xingliang Hou* (2021) EDS1-interacting J protein 1 is an essential negative regulator of plant innate immunity in Arabidopsis. The Plant Cell 33, 153-171
9. Yinyin Liao, Lanting Zeng, Shunfa Rao, Dachuan Gu, Xu Liu, Yaru Wang, Hongbo Zhu, Xingliang Hou*, and Ziyin Yang* (2020) Induced biosynthesis of chlorogenic acid in sweetpotato leaves confers the resistance against sweetpotato weevil attack. Journal of Advanced Research 24, 513-522
10. Ying Zhou#, Lanting Zeng#, Xingliang Hou, Yinyin Liao, and Ziyin Yang* (2020) Low temperature synergistically promotes wounding-induced indole accumulation by INDUCER OF CBF EXPRESSION-mediated alterations of jasmonic acid signaling in Camellia sinensis. Journal of Experimental Botany 71, 2172-2185
11. Yuge Li, Yuhua Yang, Yilong Hu, Hailun Liu, Ming He, Ziyin Yang, Fanjiang Kong, Xu Liu, and Xingliang Hou* (2019) DELLA and EDS1 form a feedback regulatory module to fine-tune plant growth-defense tradeoff in Arabidopsis. Molecular Plant 12, 1485-1498
12. He Sun, Zhu Qiao, Khi Pin Chua, Alma Tursic, Xu Liu, Yong-Gui Gao, Yuguang Mu, Xingliang Hou, and Yansong Miao* (2018) Profilin negatively regulates formin-mediated actin assembly to modulate PAMP-triggered plant immunity. Current Biology 28, 1882-1895
13. Yilong Hu, Limeng Zhou, Mingkun Huang, Xuemei He, Yuhua Yang, Xu Liu, Yuge Li, and Xingliang Hou* (2018) Gibberellins play an essential role in late embryogenesis of Arabidopsis. Nature Plants 4, 289-298
14. Xu Liu#, Yuhua Yang#, Yilong Hu, Limeng Zhou, Yuge Li, and Xingliang Hou* (2018) Temporal-specific interaction of NF-YC and CURLY LEAF during the floral transition regulates flowering. Plant Physiology 177, 105-114
15. Xu Liu and Xingliang Hou* (2018) Antagonistic regulation of ABA and GA in metabolism and signaling pathways. Frontiers in Plant Science 9, 251
16. Sijia Lu#, Xiaohui Zhao#, Yilong Hu#, Shulin Liu#, Haiyang Nan#, Xiaoming Li, Chao Fang, Dong Cao, Xinyi Shi, Lingping Kong, Tong Su, Fengge Zhang, Shichen Li, Zheng Wang, Xiaohui Yuan, Elroy R Cober, James L Weller, Baohui Liu*, Xingliang Hou*, Zhixi Tian*, and Fanjiang Kong* (2017) Natural variation at the soybean J locus improves adaptation to the tropics and enhances yield. Nature Genetics 49,773-779
17. Yang Tang#, Xuncheng Liu#, Xu Liu, Yuge Li, Keqiang Wu, and Xingliang Hou* (2017) Arabidopsis NF-YCs mediate the light-controlled hypocotyl elongation via modulating histone acetylation. Molecular Plant 10, 260-273
18. Xu Liu, Pengwei Hu, Mingkun Huang, Yang Tang, Yuge Li, Ling Li, and Xingliang Hou* (2016) The NF-YC–RGL2 module integrates GA and ABA signaling to regulate seed germination in Arabidopsis. Nature Communications 7, 12768
19. Lisha Shen#, Zhe Liang#, Xiaofeng Gu, Ying Chen, Zhi Wei Norman Teo, Xingliang Hou, Weiling Maggie Cai, Peter C. Dedon, Lu Liu, and Hao Yu* (2016) N6-Methyladenosine RNA Modification Regulates Shoot Stem Cell Fate in Arabidopsis. Developmental Cell 38, 186-200
20. Mingkun Huang, Yilong Hu, Xu Liu, Yuge Li, and Xingliang Hou* (2015) Arabidopsis LEAFY COTYLEDON1 mediates postembryonic development via interacting with PHYTOCHROME-INTERACTING FACTOR 4. The Plant Cell 27, 3099-3111
21. Mingkun Huang, Yilong Hu, Xu Liu, Yuge Li, and Xingliang Hou* (2015) Arabidopsis LEAFY COTYLEDON1 controls cell fate determination during post-embryonic development. Frontiers in Plant Science 6, 955
22. Xingliang Hou*, Jiannan Zhou, Chang Liu, Lu Liu, Lisha Shen, and Hao Yu* (2014) Nuclear factor Y-mediated H3K27me3 demethylation of the SOC1 locus orchestrates flowering responses of Arabidopsis. Nature Communications 5, 4601
23. Xingliang Hou*, Lihua Ding, and Hao Yu* (2013) Crosstalk between GA and JA signaling mediates plant growth and defense. Plant Cell Reports 32, 1067-1074
24. Lu Liu#, Chang Liu#, Xingliang Hou, Wanyan Xi, Lisha Shen, Zhen Tao, Yue Wang and Hao Yu* (2012) FTIP1 is an essential regulator required for florigen transport. PLoS Biology 10, e1001313
25. Li Yen Candy Lee#, Xingliang Hou#, Lei Fang, Shuguo Fan, Prakash P. Kumar, and Hao Yu* (2012) STUNTED mediates the control of cell proliferation by GA in Arabidopsis. Development 139, 1568-1576
26. Lei Fang, Xingliang Hou, Li Yen Candy Lee, Lu Liu, Xiaojing Yan, and Hao Yu* (2011) AtPV42a and AtPV42b redundantly regulate reproductive development in Arabidopsis thaliana. PLoS ONE 6, e19033
27. Xingliang Hou, Li Yen Candy Lee, Kuaifei Xia, Yuanyuan Yan, and Hao Yu* (2010) DELLAs modulate jasmonate signaling via competitive binding to JAZs. Developmental Cell 19, 884-894
28. Wanyan Xi#, Chang Liu#, Xingliang Hou, and Hao Yu* (2010) MOTHER OF FT AND TFL1 regulates seed germination through a negative feedback Loop modulating ABA signaling in Arabidopsis. The Plant Cell 22, 1733-1748
29. Xingliang Hou#, Wen-wei Hu#, Lisha Shen, Li Yen Candy Lee, Zhen Tao, Jinhua Han, and Hao Yu* (2008) Global identification of DELLA target genes during Arabidopsis flower development. Plant Physiology 147, 1126-1142
30. Xingliang Hou, Ping Wu*, Fangchan Jiao, Qiaojun Jia, Hanmin Chen, Jie Yu, Xinwei Song, and Keke Yi (2005) Regulation of the expression of OsIPS1 and OsIPS2 in rice via systemic and local Pi signaling and hormones. Plant Cell and Environment 28, 353–364
31. Yu Chao, Hou Xingliang, and Wu Ping* (2005) The effects of phosphorus, glucose and cytokinin on SEN1 gene expression in Arabidopsis. Acta Phytophysiologica Sinica 31, 85-89
32. Ping Wu, Ligeng Ma, Xingliang Hou, Mingyi Wang, Yunrong Wu, Feiyang Liu, and Xingwang Deng* (2003) Phosphate starvation triggers distinct alterations of genome expression in Arabidopsis roots and leaves. Plant Physiology 132, 1260-1271
参编书目：
1. Yuge Li and Xingliang Hou (2017) The Crosstalk of GA and JA: A Fine‐Tuning of the Balance of Plant Growth, Development, and Defense. Mechanism of Plant Hormone Signaling under Stress, Wiley-Blackwell, pp 127-142.